Book reviews

Pediatric & Neonatal Dosage Handbook 18th edition

Carol Taketomo, Jane Hodding, Donna Kraus

ISBN 978-1591952978 or
ISBN 978-1591952992



First published in 1992 this comprehensive guide to usage and dosing of medicines in children and neonates is now in its 19th edition. Available in two editions – with and without an International Trade Names Index, the former listing drug trade names form over 100 countries – the books contains 944 comprehensive monographs, with 16 new to this edition, with a vast amount of information for each drug, e.g. the gentamicin monographs runs to two and a half pages. Over 100 monographs contain an extemporaneous formulation to prepare a liquid solution where no licensed product is available

In addition to the drug monographs there are nearly 300 pages of appendices covering topics such as compatibility of chemotherapy and related support medications, paediatric HIV, carbohydrate content of medication and a new appendix containing the WHO model formulary for children

Drug monographs are arranged alphabetically, by generic name, but the book also contains a therapeutic category and key word index listing, e.g. all preservative free medicines together.

Previously known as the ‘Pediatric Dosage Handbook’ the 18th edition includes a separate neonatal dosing field in over 250 monographs, which allows easy access to specific neonatal dosing. To emphasise the change the title of the book has been changed.

The book is available for purchase at at £41.13 (ISBN 978-1591952978) or at $58.12 for the International Trade Names Index edition (ISBN 978-1591952992). Whilst not pocket size, and it would be impossible to fit the 1900 pages of information contained in this volume into a pocket sized edition, this book is a very useful addition to the neonatal and paediatric pharmacist’s knowledge resources and should be on the shelf of anyone using medicines in this speciality.

Manual of Childhood Infections: The Blue Book (Oxford Specialist Handbooks in Paediatrics) Mike Sharland, Andrew Cant, Delane Shingadia and E. Graham Davies















The new, 3rd, edition was published in April 2011. ISBN 978-0199573585, it can be purchased at for £33.20.

Did you know……….

  • Respiratory syncytial virus (RSV) accounts for over 50% of all cases of bronchiolitis….. studies have shown that adrenaline, bronchodilators and oral, inhaled and IV steroids offer no benefit and may even be harmful in the acute phase.
  • Haemolytic uraemic syndrome (HUS) can be clinically classified into
    • Diarrhoea associated (D+) or typical
    • Without diarrhoea (D-) or atypical.

In the UK most D+ HUS is caused by E.Coli H7 0157 strain. Supportive management is of key importance; antimotility agents should be avoided as by reducing gut motility there is prolonged contact of the pathogenic bacteria with the intestinal mucosa.  Antibiotics for gut decontamination are not recommended.

All this, and much, much more…….in this excellent little book. It was produced by the European Society for Paediatric Infectious Diseases in collaboration with The Royal College of Paediatrics and Child Health. The book is split into two sections: Clinical Syndromes and Specific Infections and for each pulls together Epidemiology, Clinical Manifestations, Investigation and Management of a multitude of common childhood infections. There is fascinating background information for each chapter supported by up to date management considerations including reference to new agents being trialled. There are also references at the end of each section for further reading.

The book has some useful Appendices for example:

  • Guidance on infection control in schools (recommended time period a child should stay away from school, nursery or childminders)
  • Immunisation of the Child
  • Formulary (Medicines Guide)

This Medicines Guide was drawn up using expertise from NPPG members and is designed to complement rather than replace individual country specific formularies such as BNF for Children.

My only minor criticism is that there appear to be some gaps. For example, I could not find reference to cystic fibrosis and empyema does not appear in the index (but is mentioned in the section on lower respiratory tract infections).

Overall, – this is a great book and good value for money. It is highly recommended to have in any pharmacy, particularly if you have junior or trainee Pharmacists in Child Health. As a pharmacist experienced in Paediatrics I have already used it loads of times!

Rowena McArtney, Jan 2012

Guide to Paediatric Clinical Research- Editors Klaus Rose, John N van den Anker


US government and the EU have made it mandatory for the pharmaceutical industry to investigate medicines in children, thus exposing a multitude of different institutions to paediatric research. Written by exponents of academia as well as the pharmaceutical industry, regulators and patient ad­vocacy groups, this book explains the background of the US and EU paediatric legislations, gives an analysis of their probable short-, mid- and long-term impact, addresses key operational challenges in paediatric research, and develops a tentative vision where paediatric drug development needs to go.

Helping to understand the role of the different stakeholders, the spectrum of readers to profit from this book ranges from paedia­tricians, general medical personnel and pharmacologists to those involved in regulatory affairs and clinical trials, pharmaceutical company management, patient advocacy groups, ethical commit­tees, politicians and interested lay persons.

For a table of contents and a preview of each section go to\paediatricguide ISBN: 978-3-8055-8201-8 €65.50

Practical Algorithms In Pediatric Nephrology
Editors – Zelikovic I, Eisenstein I

This book is meant as a pragmatic text for use at the patient's bedside. It classifies common clinical symptoms and signs, laboratory abnormalities and issues of man­agement as they present themselves in daily practice. Special emphasis is given to new knowledge that has accumulated on the molecular pathophysiology and molecular genetics of various kidney diseases in order to deepen and strengthen the practical approach to common problems in pediatric nephrology.  .

Aimed at an audience of general and family practitioners, pediatricians and trainees who are not exposed on a day-to-day basis to pediatric nephrology problems, it provides a logical, concise and cost-effective approach from which they can profit and acquire medical reasoning. 

Further information at ISBN978-3-8055-8539-2 €38